ATRT-23. SIRT2 cooperates with SMARCB1 to induce a differentiation block in ATRT

Atypical Teratoid Rhabdoid Tumor is a highly aggressive pediatric brain tumor with poor prognosis driven by loss of the chromatin remodeling factor SMARCB1 that is responsible for determining cellular pluripotency and lineage commitment. The mechanisms by which SMARCB1 deletion results in tumorigene...

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Detalles Bibliográficos
Autores principales: Alimova, Irina, Wang, Dong, Pierce, Angela, Lakshmanachetty, Senthilnath, Prince, Eric, Danis, Etienne, Serkova, Natalie, Madhavan, Krishna, Balakrishnan, Ilango, Yang, Min, Lin, Henning, Foreman, Nicholas, Venkataraman, Sujatha, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Atypical Teratoid Rhabdoid Tumor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165152/
http://dx.doi.org/10.1093/neuonc/noac079.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165152/
http://dx.doi.org/10.1093/neuonc/noac079.022

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