MEDB-65. Molecular subclassification of a national cohort of pediatric medulloblastoma based on methylation profile

INTRODUCTION: Pediatric Medulloblastoma (MB) accounts for approximately 20% of all childhood brain tumors. Molecular subgroups namely WNT, SHH, Group 3 and Group 4, exhibit divergent biology, and clinical outcomes. DNA methylation analysis is a robust option to classify pediatric MB into molecular s...

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Detalles Bibliográficos
Autores principales: Alaña, Lide, Martin-Guerrero, Idoia, Navajas, Aurora, Zaldumbide, Laura, Mosteiro, Lorena, Schwalbe, Edward C, Hicks, Debbie, Clifford, Steven C, García-Ariza, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Medulloblastoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165213/
http://dx.doi.org/10.1093/neuonc/noac079.439

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