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ETMR-05. Single-cell transcriptomics of ETMR reveals developmental cellular programs and tumor-pericyte communications in the microenvironment
BACKGROUND: Embryonal tumors with multilayered rosettes (ETMR) are pediatric brain tumors bearing a grim prognosis, despite intensive multimodal therapeutic approaches. Insights into cellular heterogeneity and cellular communication of tumor cells with cells of the tumor microenvironment (TME), by a...
Autores principales: | de Faria, Flavia W, Walter, Carolin, Interlandi, Marta, Melcher, Viktoria, Riedel, Nicole, Graf, Monika, Moreno, Natalia, Schoof, Melanie, Holdhof, Dörthe, Thomas, Christian, Frühwald, Michael C, Maerkl, Bruno, Ho, Ben, Sandmann, Sarah, Varghese, Julian, Ebinger, Martin, Schuhmann, Martin, Canak, Aysegül, Huang, Annie, Schüller, Ulrich, Albert, Thomas K, Kerl, Kornelius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165314/ http://dx.doi.org/10.1093/neuonc/noac079.183 |
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