MEDB-41. Identifying a subgroup of patients with early childhood sonic hedgehog-activated medulloblastoma with unfavorable prognosis after treatment with radiation-sparing regimens including intraventricular methotrexate

PURPOSE/METHODS: Clinical and molecular risk factors in 142 patients <5 years with desmoplastic medulloblastoma (DMB) or medulloblastoma with extensive nodularity (MBEN) were investigated. Patients were diagnosed between 1992 and 2020 and treated with radiation-sparing approaches, 131 with intrav...

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Detalles Bibliográficos
Autores principales: Tonn, Svenja, Obrecht, Denise, Sill, Martin, Spohn, Michael, Milde, Till, Pietsch, Torsten, Bison, Brigitte, Juhnke, Björn-Ole, Struve, Nina, Friedrich, Carsten, von Bueren, André O, Gerber, Nicolas U, Benesch, Martin, Jäger, Natalie, Kool, Marcel, Korshunov, Andrey, Schüller, Ulrich, Pfister, Stefan M, Rutkowski, Stefan, Mynarek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Medulloblastoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165318/
http://dx.doi.org/10.1093/neuonc/noac079.415

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