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MEDB-49. Relapsed SHH medulloblastomas in young children. Are there alternatives to full-dose craniospinal irradiation?

BACKGROUND/RATIONAL: Following initial irradiation sparing therapy, many young children with relapsed medulloblastoma can be salvaged with craniospinal irradiation (CSI). However, the interval to relapse is short and neurocognitive sequelae remain a major concern. The contribution of molecular subgr...

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Detalles Bibliográficos
Autores principales: Erker, Craig, Craig, Brandon, Bailey, Simon, Massimino, Maura, Larouche, Valerie, L Finlay, Jonathan, Kline, Cassie, Michaiel, George, Margol, Ashley, Cohen, Kenneth, Cacciotti, Chantel, Harrods, Virginia, Doris, Kathleen, AbdelBaki, Mohammed, Amayiri, Nisreen, Wang, Zhihong, Hansford, Jordan, Hukin, Juliette, Salloum, Ralph, Hoffman, Lindsay, Muray, Jeffrey, Ginn, Kevin, Zapotocky, Zapotocky, Baroni, Lorena, Ramaswamy, Vijay, Gilheens, Stephen, Aguiera, Dolli, Mazewski, Claire, Shah, Shafqat, Strother, Douglas, Muller, Sabine, Gajjar, Amar, Northcott, Paul, Clifford, Steve, Robinson, Giles, Bouffet, Eric, Lafay-Cousin, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165324/
http://dx.doi.org/10.1093/neuonc/noac079.423