DIPG-61. Preclinical efficacy of combined radiotherapy with venetoclax treatment in targeting diffuse midline gliomas

BACKGROUND: H3K27M diffuse midline gliomas (DMGs) are highly aggressive pediatric tumors of pons, thalamus or spinal cord. The only standard-of-care for DMGs is radiation therapy (RT) since the anatomical location of such tumors does not allow surgical resection. Tumor response to RT is at best tran...

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Detalles Bibliográficos
Autores principales: Madhavan, Krishna, Balakrishnan, Ilango, Lakshmanachetty, Senthilnath, Pierce, Angela, Sanford, Bridget, Fosmire, Susan, Elajaili, Hanan, Walker, Faye, Wang, Dong, Nozik-Grayck, Eva, Mitra, Siddhartha, Dahl, Nathan, Vibhakar, Rajeev, Venkataraman, Sujatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165325/
http://dx.doi.org/10.1093/neuonc/noac079.118

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