HGG-37. A case ofETV6-NTRK3 fusion driven infantile hemispheric glioma (IHG) with acquired drug resistance against first- and second-generation NTRK-inhibitors

A 3-month-old girl had left cerebral infantile hemispheric glioma (IHG), H3 wild type (wt), Grade IV (WHO2020) with diffuse leptomeningeal and spinal metastasis. Craniotomies were performed twice which achieved partial resection. Histopathology revealed high grade glioma, Ki67 30-40%, mitosis and wi...

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Detalles Bibliográficos
Autores principales: Ku, Dennis T L, Liu, Anthony P Y, Kan, Amanda N C, Yuen, Liz Y P, Shing, M K, Yan, Carol Y L, Fu, Eric, Yau, Jeffrey P W, Luk, C W, Ng, H K, Chan, Godfrey C F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165344/
http://dx.doi.org/10.1093/neuonc/noac079.252

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