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HGG-62. Molecularly guided treatment of mismatch repair-deficient pediatric brain tumors

Mismatch repair (MMR)-deficient brain tumors, defined by high tumor mutational burden (TMB) and alterations in MMR or DNA proofreading genes, may harbor therapeutic vulnerabilities to immune checkpoint inhibition (ICI) and resistance to temozolomide. We report a single-institution experience incorpo...

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Detalles Bibliográficos
Autores principales:	Crotty, Erin, Cole, Bonnie, Stasi, Shannon, Vitanza, Nicholas, Paulson, Vera, Lockwood, Christina, Leary, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	High Grade Glioma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165347/ http://dx.doi.org/10.1093/neuonc/noac079.277

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