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LGG-54. Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

To elucidate the mechanisms underlying the reduced incidence of brain tumors in children with Neurofibromatosis type 1 (NF1) and asthma, we leverage optic pathway glioma (Nf1-OPG) mice, human and mouse RNAseq data, and two different experimental asthma models. Following ovalbumin or house dust mite...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Jit, Sanapala, Shilpa, Cobb, Olivia, Bewley, Alice, Cordell, Elizabeth, Garbow, Joel, Holtzman, Michael, Gutmann, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Low Grade Glioma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165416/ http://dx.doi.org/10.1093/neuonc/noac079.366

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