Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)

Acoustofluidic Stimulation of Functional Immune Cells In article number 2105809, Jinsoo Park, Hyung Jin Sung, Jessie S. Jeon, and co‐workers employ surface acoustic waves to agitate fluid in a microreactor capable of dynamic cell culture in a controllable and contact‐free manner. This microreactor p...

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Detalles Bibliográficos
Autores principales: Kim, Seunggyu, Nam, Hyeono, Cha, Beomseok, Park, Jinsoo, Sung, Hyung Jin, Jeon, Jessie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165476/
http://dx.doi.org/10.1002/advs.202270102
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author Kim, Seunggyu
Nam, Hyeono
Cha, Beomseok
Park, Jinsoo
Sung, Hyung Jin
Jeon, Jessie S.
author_facet Kim, Seunggyu
Nam, Hyeono
Cha, Beomseok
Park, Jinsoo
Sung, Hyung Jin
Jeon, Jessie S.
author_sort Kim, Seunggyu
collection PubMed
description Acoustofluidic Stimulation of Functional Immune Cells In article number 2105809, Jinsoo Park, Hyung Jin Sung, Jessie S. Jeon, and co‐workers employ surface acoustic waves to agitate fluid in a microreactor capable of dynamic cell culture in a controllable and contact‐free manner. This microreactor prevents cellular damages that can be seen in the acoustic vortex by adjusting the duty cycle and applied power of the acoustical actuation. Using the microreactor, the functional changes of natural killer cells are observed upon the acoustical stimulation, namely, Ca(2+) influx to the cells and their enhanced cell‐mediated cytotoxicity to the tumor cells in the copresence of protein kinase C activator. [Image: see text]
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spelling pubmed-91654762022-06-04 Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022) Kim, Seunggyu Nam, Hyeono Cha, Beomseok Park, Jinsoo Sung, Hyung Jin Jeon, Jessie S. Adv Sci (Weinh) Inside Front Cover Acoustofluidic Stimulation of Functional Immune Cells In article number 2105809, Jinsoo Park, Hyung Jin Sung, Jessie S. Jeon, and co‐workers employ surface acoustic waves to agitate fluid in a microreactor capable of dynamic cell culture in a controllable and contact‐free manner. This microreactor prevents cellular damages that can be seen in the acoustic vortex by adjusting the duty cycle and applied power of the acoustical actuation. Using the microreactor, the functional changes of natural killer cells are observed upon the acoustical stimulation, namely, Ca(2+) influx to the cells and their enhanced cell‐mediated cytotoxicity to the tumor cells in the copresence of protein kinase C activator. [Image: see text] John Wiley and Sons Inc. 2022-06-03 /pmc/articles/PMC9165476/ http://dx.doi.org/10.1002/advs.202270102 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Front Cover
Kim, Seunggyu
Nam, Hyeono
Cha, Beomseok
Park, Jinsoo
Sung, Hyung Jin
Jeon, Jessie S.
Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)
title Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)
title_full Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)
title_fullStr Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)
title_full_unstemmed Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)
title_short Acoustofluidic Stimulation of Functional Immune Cells in a Microreactor (Adv. Sci. 16/2022)
title_sort acoustofluidic stimulation of functional immune cells in a microreactor (adv. sci. 16/2022)
topic Inside Front Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165476/
http://dx.doi.org/10.1002/advs.202270102
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