Cargando…

Monocyte NLRP3‐IL‐1β Hyperactivation Mediates Neuronal and Synaptic Dysfunction in Perioperative Neurocognitive Disorder

Perioperative neurocognitive disorder may develop in vulnerable patients following major operation. While neuroinflammation is linked to the cognitive effects of surgery, how surgery and immune signaling modulate neuronal circuits, leading to learning and memory impairment remains unknown. Using in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Kai, Hu, Qiuping, Xie, Zhongcong, Yang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165480/ https://www.ncbi.nlm.nih.gov/pubmed/35347900 http://dx.doi.org/10.1002/advs.202104106

Ejemplares similares

AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
por: Belforte, Nicolas, et al.
Publicado: (2021)

Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects
por: Tomasoni, Romana, et al.
Publicado: (2017)

Perioperative neurocognitive dysfunction: thinking from the gut?
por: Xu, Xiaolin, et al.
Publicado: (2020)

Dysfunction of the Glymphatic System as a Potential Mechanism of Perioperative Neurocognitive Disorders
por: Ren, Xuli, et al.
Publicado: (2021)

Inhibition of unfolded protein response prevents post‐anesthesia neuronal hyperactivity and synapse loss in aged mice
por: Chen, Kai, et al.
Publicado: (2022)

The NLRP3 inflammasome is a potential mechanism and therapeutic target for perioperative neurocognitive disorders
por: Li, Jiayue, et al.
Publicado: (2023)

Resveratrol Preconditioning Protects Against Ischemia-Induced Synaptic Dysfunction and Cofilin Hyperactivation in the Mouse Hippocampal Slice
por: Escobar, Iris, et al.
Publicado: (2023)

Role of P2X4/NLRP3 Pathway-Mediated Neuroinflammation in Perioperative Neurocognitive Disorders
por: Yuan, Hui, et al.
Publicado: (2022)

The Role of Gut Microbiota—Gut—Brain Axis in Perioperative Neurocognitive Dysfunction
por: Lu, Jian, et al.
Publicado: (2022)

The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis
por: Madonna, Stefania, et al.
Publicado: (2019)

Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease
por: Munawara, Usma, et al.
Publicado: (2021)

Propionibacterium acnes induces IL-1β secretion via the NLRP3 inflammasome in human monocytes
por: Qin, Min, et al.
Publicado: (2013)

Neuroinflammation and Perioperative Neurocognitive Disorders
por: Subramaniyan, Saraswathi, et al.
Publicado: (2019)

Intergenerational Perioperative Neurocognitive Disorder
por: Ju, Ling-Sha, et al.
Publicado: (2023)

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice
por: Bourne, Joshua H., et al.
Publicado: (2023)

Dexmedetomidine Mitigated NLRP3-Mediated Neuroinflammation via the Ubiquitin-Autophagy Pathway to Improve Perioperative Neurocognitive Disorder in Mice
por: Zhang, Lieliang, et al.
Publicado: (2021)

Mechanisms of neuronal dysfunction in HIV-associated neurocognitive disorders
por: Irollo, Elena, et al.
Publicado: (2021)

The Role of Microglia in Perioperative Neurocognitive Disorders
por: Fan, Wenguo, et al.
Publicado: (2020)

Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation
por: Tanaka, Shoji
Publicado: (2008)

NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats
por: Chen, Lin, et al.
Publicado: (2019)

Acetate attenuates perioperative neurocognitive disorders in aged mice
por: Wen, Cen, et al.
Publicado: (2020)

The Role of Perioperative Sleep Disturbance in Postoperative Neurocognitive Disorders
por: Wang, Xuan, et al.
Publicado: (2021)

Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages
por: Zhu, Lijun, et al.
Publicado: (2022)

α-Synuclein-containing erythrocytic extracellular vesicles: essential contributors to hyperactivation of monocytes in Parkinson’s disease
por: Liu, Zongran, et al.
Publicado: (2022)

The Role of Microglia in Perioperative Neuroinflammation and Neurocognitive Disorders
por: Saxena, Sarah, et al.
Publicado: (2021)

The Role of Astrocytes in the Mechanism of Perioperative Neurocognitive Disorders
por: Cao, Ying, et al.
Publicado: (2022)

Endothelial Dysfunction and Platelet Hyperactivation in Diabetic Complications Induced by Glycemic Variability
por: Huang, Ye, et al.
Publicado: (2022)

Ginsenoside compound K reduces neuronal damage and improves neuronal synaptic dysfunction by targeting Aβ
por: Li, Na, et al.
Publicado: (2023)

The role of neuronal calcium sensors in balancing synaptic plasticity and synaptic dysfunction
por: Kerrigan, Talitha L., et al.
Publicado: (2012)

Same pollution sources for climate change might be hyperactivating the NLRP3 inflammasome and exacerbating neuroinflammation and SARS mortality
por: Macias-Verde, David, et al.
Publicado: (2021)

Neurocognitive Dysfunction Risk Alleviation With the Use of Dexmedetomidine in Perioperative Conditions or as ICU Sedation: A Meta-Analysis
por: Li, Bo, et al.
Publicado: (2015)

Dynamic Nomogram for Predicting the Risk of Perioperative Neurocognitive Disorders in Adults
por: Song, Ai-lin, et al.
Publicado: (2023)

Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation
por: Liu, Ya-Fei, et al.
Publicado: (2016)

IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice
por: Ni, Pengfei, et al.
Publicado: (2018)

HIV and Neurocognitive Dysfunction
por: Spudich, Serena
Publicado: (2013)

Renin-Angiotensin System Hyperactivation Can Induce Inflammation and Retinal Neural Dysfunction
por: Kurihara, Toshihide, et al.
Publicado: (2012)

Complement activation contributes to perioperative neurocognitive disorders in mice
por: Xiong, Chao, et al.
Publicado: (2018)

Neuroinflammation in perioperative neurocognitive disorders: From bench to the bedside
por: Liu, Yang, et al.
Publicado: (2022)

Mitigation of perioperative neurocognitive disorders: A holistic approach
por: Safavynia, Seyed A., et al.
Publicado: (2022)

Microglia Remodelling and Neuroinflammation Parallel Neuronal Hyperactivation Following Acute Organophosphate Poisoning
por: Somkhit, Julie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_33uuro8e65l3mu2d7o4vrb1tka