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RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13

The subcellular localization and intracellular trafficking of Toll‐like receptors (TLRs) critically regulate TLRs‐mediated antimicrobial immunity and autoimmunity. Here, it is demonstrated that the E3 ubiquitin ligase RNF115 inhibits the post‐endoplasmic reticulum (ER) trafficking of TLRs and TLRs‐m...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhi‐Dong, Li, Hong‐Xu, Gan, Hu, Tang, Zhen, Guo, Yu‐Yao, Yao, Shu‐Qi, Liuyu, Tianzi, Zhong, Bo, Lin, Dandan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165487/ https://www.ncbi.nlm.nih.gov/pubmed/35343654 http://dx.doi.org/10.1002/advs.202105391

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