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Dermatology: how to manage facial hyperpigmentation in skin of colour

Hyperpigmentation disorders, such as post-inflammatory hyperpigmentation and melasma, are common conditions affecting all skin types. These conditions are largely benign and are influenced by numerous endogenous and exogenous factors impacting melanocyte activity and melanin production. Current trea...

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Detalles Bibliográficos
Autores principales: Moolla, Siddiq, Miller-Monthrope, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioExcel Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165630/
https://www.ncbi.nlm.nih.gov/pubmed/35720052
http://dx.doi.org/10.7573/dic.2021-11-2
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author Moolla, Siddiq
Miller-Monthrope, Yvette
author_facet Moolla, Siddiq
Miller-Monthrope, Yvette
author_sort Moolla, Siddiq
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description Hyperpigmentation disorders, such as post-inflammatory hyperpigmentation and melasma, are common conditions affecting all skin types. These conditions are largely benign and are influenced by numerous endogenous and exogenous factors impacting melanocyte activity and melanin production. Current treatment modalities for these conditions fall into broad categories, including photoprotection, topical and systemic therapies, chemical peels, and laser or light-based therapies. Biological differences in skin of colour require additional consideration when deciding on treatment and management. This narrative review provides an inclusive summary of these conditions and compares the current treatment options with a specific focus on skin of colour. Photoprotection and sunscreens protective against both UV and visible light are recommended for all individuals. Topical therapy is the recommended first-line treatment, with the gold standard being hydroquinone, which can be used alone or in combination with other agents. Chemical peels and laser or light-based therapies are also effective adjunctive methods of treatment; however, caution should be taken when used in patients with richly pigmented skin due to the increased risk of post-inflammatory hyperpigmentation.
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spelling pubmed-91656302022-06-16 Dermatology: how to manage facial hyperpigmentation in skin of colour Moolla, Siddiq Miller-Monthrope, Yvette Drugs Context Review Hyperpigmentation disorders, such as post-inflammatory hyperpigmentation and melasma, are common conditions affecting all skin types. These conditions are largely benign and are influenced by numerous endogenous and exogenous factors impacting melanocyte activity and melanin production. Current treatment modalities for these conditions fall into broad categories, including photoprotection, topical and systemic therapies, chemical peels, and laser or light-based therapies. Biological differences in skin of colour require additional consideration when deciding on treatment and management. This narrative review provides an inclusive summary of these conditions and compares the current treatment options with a specific focus on skin of colour. Photoprotection and sunscreens protective against both UV and visible light are recommended for all individuals. Topical therapy is the recommended first-line treatment, with the gold standard being hydroquinone, which can be used alone or in combination with other agents. Chemical peels and laser or light-based therapies are also effective adjunctive methods of treatment; however, caution should be taken when used in patients with richly pigmented skin due to the increased risk of post-inflammatory hyperpigmentation. BioExcel Publishing Ltd 2022-05-31 /pmc/articles/PMC9165630/ /pubmed/35720052 http://dx.doi.org/10.7573/dic.2021-11-2 Text en Copyright © 2022 Moolla S, Miller-Monthrope Y https://creativecommons.org/licenses/by-nc-nd/4.0/Published by Drugs in Context under Creative Commons License Deed CC BY NC ND 4.0, which allows anyone to copy, distribute and transmit the article provided it is properly attributed in the manner specified below. No commercial use without permission.
spellingShingle Review
Moolla, Siddiq
Miller-Monthrope, Yvette
Dermatology: how to manage facial hyperpigmentation in skin of colour
title Dermatology: how to manage facial hyperpigmentation in skin of colour
title_full Dermatology: how to manage facial hyperpigmentation in skin of colour
title_fullStr Dermatology: how to manage facial hyperpigmentation in skin of colour
title_full_unstemmed Dermatology: how to manage facial hyperpigmentation in skin of colour
title_short Dermatology: how to manage facial hyperpigmentation in skin of colour
title_sort dermatology: how to manage facial hyperpigmentation in skin of colour
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165630/
https://www.ncbi.nlm.nih.gov/pubmed/35720052
http://dx.doi.org/10.7573/dic.2021-11-2
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