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Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line
Evaluating novel compounds for neuroprotective effects in animal models of traumatic brain injury (TBI) is a protracted, labor-intensive and costly effort. However, the present lack of effective treatment options for TBI, despite decades of research, shows the critical need for alternative methods f...
Autores principales: | Weisz, Harris A., Boone, Deborah R., Coggins, William S., Edwards, Gabrielle A., Willey, Hannah E., Widen, Steven G., Siegel, Dionicio, Nelson, Andrew T., Prough, Donald S., Hellmich, Helen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165808/ https://www.ncbi.nlm.nih.gov/pubmed/35657963 http://dx.doi.org/10.1371/journal.pone.0267682 |
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