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A mathematical model of in vitro hepatocellular cholesterol and lipoprotein metabolism for hyperlipidemia therapy

Cardiovascular diseases associated with high cholesterol (hypercholesterolemia) and low-density lipoproteins (LDL) levels are significant contributors to total mortality in developing and developed countries. Mathematical modeling of LDL metabolism is an important step in the development of drugs fo...

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Detalles Bibliográficos
Autores principales:	Efremov, Yuri, Ermolaeva, Anastasia, Vladimirov, Georgiy, Gordleeva, Susanna, Svistunov, Andrey, Zaikin, Alexey, Timashev, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165868/ https://www.ncbi.nlm.nih.gov/pubmed/35657919 http://dx.doi.org/10.1371/journal.pone.0264903

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