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Integrating (1)H MRS and deuterium labeled glucose for mapping the dynamics of neural metabolism in humans

In the technique presented here, dubbed ‘qMRS’, we quantify the change in (1)H MRS signal following administration of (2)H-labeled glucose. As in recent human DMRS studies, we administer [6,6′−(2)H(2)]-glucose orally to healthy subjects. Since (2)H is not detectable by (1)H MRS, the transfer of the...

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Detalles Bibliográficos
Autores principales: Cember, Abigail T.J., Wilson, Neil E., Rich, Laurie J., Bagga, Puneet, Nanga, Ravi Prakash Reddy, Swago, Sophia, Swain, Anshuman, Thakuri, Deepa, Elliot, Mark, Schnall, Mitchell D., Detre, John A., Reddy, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166154/
https://www.ncbi.nlm.nih.gov/pubmed/35143973
http://dx.doi.org/10.1016/j.neuroimage.2022.118977

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