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Vitamin C and its therapeutic potential in the management of COVID19

COVID19 has emerged as one of the worst pandemics in the history of mankind. Several vaccines have been approved by different government agencies worldwide, but data on their efficacy and safety are limited, and distribution remains a massive challenge. As per WHO, personal immunity is vital for pro...

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Autores principales: RS, Neethu, Reddy, M.V.N. Janardhan, Batra, Sakshi, Srivastava, Sunil Kumar, Syal, Kirtimaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166267/
https://www.ncbi.nlm.nih.gov/pubmed/35871955
http://dx.doi.org/10.1016/j.clnesp.2022.05.026
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author RS, Neethu
Reddy, M.V.N. Janardhan
Batra, Sakshi
Srivastava, Sunil Kumar
Syal, Kirtimaan
author_facet RS, Neethu
Reddy, M.V.N. Janardhan
Batra, Sakshi
Srivastava, Sunil Kumar
Syal, Kirtimaan
author_sort RS, Neethu
collection PubMed
description COVID19 has emerged as one of the worst pandemics in the history of mankind. Several vaccines have been approved by different government agencies worldwide, but data on their efficacy and safety are limited, and distribution remains a massive challenge. As per WHO, personal immunity is vital for protection against COVID19. Earlier, Vitamin C-mediated pathways have been shown to play critical role in boosting immunity attributed to its antioxidant properties. Recently, the involvement of such pathways in protection against COVID19 has been suggested. The controlled doses of Vitamin C administered through intravenous (IV) injections are being studied for determining its role in the prognosis of COVID19. In this article, we have discussed the potential role of Vitamin C in the management in COVID19 patients and presented recent clinical trials data. Additionally, we have elaborated the possibility of administering Vitamin C through inhalers in order to achieve local high concentration and the challenges of such approach.
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spelling pubmed-91662672022-06-07 Vitamin C and its therapeutic potential in the management of COVID19 RS, Neethu Reddy, M.V.N. Janardhan Batra, Sakshi Srivastava, Sunil Kumar Syal, Kirtimaan Clin Nutr ESPEN Narrative Review COVID19 has emerged as one of the worst pandemics in the history of mankind. Several vaccines have been approved by different government agencies worldwide, but data on their efficacy and safety are limited, and distribution remains a massive challenge. As per WHO, personal immunity is vital for protection against COVID19. Earlier, Vitamin C-mediated pathways have been shown to play critical role in boosting immunity attributed to its antioxidant properties. Recently, the involvement of such pathways in protection against COVID19 has been suggested. The controlled doses of Vitamin C administered through intravenous (IV) injections are being studied for determining its role in the prognosis of COVID19. In this article, we have discussed the potential role of Vitamin C in the management in COVID19 patients and presented recent clinical trials data. Additionally, we have elaborated the possibility of administering Vitamin C through inhalers in order to achieve local high concentration and the challenges of such approach. European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. 2022-08 2022-06-04 /pmc/articles/PMC9166267/ /pubmed/35871955 http://dx.doi.org/10.1016/j.clnesp.2022.05.026 Text en © 2022 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Narrative Review
RS, Neethu
Reddy, M.V.N. Janardhan
Batra, Sakshi
Srivastava, Sunil Kumar
Syal, Kirtimaan
Vitamin C and its therapeutic potential in the management of COVID19
title Vitamin C and its therapeutic potential in the management of COVID19
title_full Vitamin C and its therapeutic potential in the management of COVID19
title_fullStr Vitamin C and its therapeutic potential in the management of COVID19
title_full_unstemmed Vitamin C and its therapeutic potential in the management of COVID19
title_short Vitamin C and its therapeutic potential in the management of COVID19
title_sort vitamin c and its therapeutic potential in the management of covid19
topic Narrative Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166267/
https://www.ncbi.nlm.nih.gov/pubmed/35871955
http://dx.doi.org/10.1016/j.clnesp.2022.05.026
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