The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels

Godellas and Grosman revisit equilibrium binding assays to shed new light on pentameric ligand-gated ion channels.

Detalles Bibliográficos
Autores principales: Middendorf, Thomas R., Goldschen-Ohm, Marcel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166280/
https://www.ncbi.nlm.nih.gov/pubmed/35653137
http://dx.doi.org/10.1085/jgp.202213177
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author Middendorf, Thomas R.
Goldschen-Ohm, Marcel P.
author_facet Middendorf, Thomas R.
Goldschen-Ohm, Marcel P.
author_sort Middendorf, Thomas R.
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description Godellas and Grosman revisit equilibrium binding assays to shed new light on pentameric ligand-gated ion channels.
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spelling pubmed-91662802023-01-04 The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels Middendorf, Thomas R. Goldschen-Ohm, Marcel P. J Gen Physiol Commentary Godellas and Grosman revisit equilibrium binding assays to shed new light on pentameric ligand-gated ion channels. Rockefeller University Press 2022-06-02 /pmc/articles/PMC9166280/ /pubmed/35653137 http://dx.doi.org/10.1085/jgp.202213177 Text en © 2022 Middendorf and Goldschen-Ohm https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Middendorf, Thomas R.
Goldschen-Ohm, Marcel P.
The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
title The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
title_full The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
title_fullStr The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
title_full_unstemmed The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
title_short The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
title_sort surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166280/
https://www.ncbi.nlm.nih.gov/pubmed/35653137
http://dx.doi.org/10.1085/jgp.202213177
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