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Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity

Flavanols are privileged heterocyclic compounds in medicinal chemistry. It is notable to develop an efficient and straightforward protocol for accessing chiral flavanols with precise control of the stereocenters. Here, a highly efficient kinetic resolution of chromenes was reported via Cu-catalyzed...

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Detalles Bibliográficos
Autores principales:	Yang, Qingjing, Wang, Zihao, Hor, Catherine Hong Huan, Xiao, Haitao, Bian, Zhaoxiang, Wang, Jun (Joelle)
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Physical and Materials Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166297/ https://www.ncbi.nlm.nih.gov/pubmed/35658029 http://dx.doi.org/10.1126/sciadv.abm9603

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