Modeling binding specificities of transcription factor pairs with random forests

BACKGROUND: Transcription factors (TFs) bind regulatory DNA regions with sequence specificity, form complexes and regulate gene expression. In cooperative TF-TF binding, two transcription factors bind onto a shared DNA binding site as a pair. Previous work has demonstrated pairwise TF-TF-DNA interac...

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Detalles Bibliográficos
Autores principales: Antikainen, Anni A., Heinonen, Markus, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166390/
https://www.ncbi.nlm.nih.gov/pubmed/35659235
http://dx.doi.org/10.1186/s12859-022-04734-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166390/
https://www.ncbi.nlm.nih.gov/pubmed/35659235
http://dx.doi.org/10.1186/s12859-022-04734-7

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