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TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target
Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane immune receptor that is mainly expressed on microglia in the brain and macrophages in the periphery. Recent studies have identified TREM2 as a risk factor for Alzheimer’s disease (AD). Increasing evidence has sho...
Autores principales: | Li, Rui-Yang, Qin, Qi, Yang, Han-Chen, Wang, Ying-Ying, Mi, Ying-Xin, Yin, Yun-Si, Wang, Meng, Yu, Chao-Ji, Tang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166437/ https://www.ncbi.nlm.nih.gov/pubmed/35658903 http://dx.doi.org/10.1186/s13024-022-00542-y |
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