Orally Administered Halofuginone-Loaded TPGS Polymeric Micelles Against Triple-Negative Breast Cancer: Enhanced Absorption and Efficacy with Reduced Toxicity and Metastasis

BACKGROUND: Halofuginone (HF)-loaded TPGS polymeric micelles (HTPM) were successfully fabricated using the thin-film hydration technique. HTPM via intravenous injection have been demonstrated to exert an excellent anticancer effect against triple-negative breast cancer (TNBC) cells and subcutaneous...

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Detalles Bibliográficos
Autores principales: Zuo, Runan, Zhang, Yan, Chen, Xiaorong, Hu, Shiheng, Song, Xinhao, Gao, Xiuge, Gong, Jiahao, Ji, Hui, Yang, Fengzhu, Peng, Lin, Fang, Kun, Lv, Yingjun, Zhang, Junren, Jiang, Shanxiang, Guo, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166452/
https://www.ncbi.nlm.nih.gov/pubmed/35668999
http://dx.doi.org/10.2147/IJN.S352538

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