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Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome

Hepatopulmonary syndrome is a phenomenon that results in an intrapulmonary shunt leading to dyspnea and hypoxemia with poor response to oxygen supplementation. It is now an indication for liver transplantation; however, some transplants result in subsequent pulmonary hypertension. Postulated mechani...

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Detalles Bibliográficos
Autores principales: Dadlani, Apaar, Eiswerth, Michael, Bosch, Armando, Sharpe, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166458/
https://www.ncbi.nlm.nih.gov/pubmed/35676995
http://dx.doi.org/10.7759/cureus.24740
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author Dadlani, Apaar
Eiswerth, Michael
Bosch, Armando
Sharpe, Tyler
author_facet Dadlani, Apaar
Eiswerth, Michael
Bosch, Armando
Sharpe, Tyler
author_sort Dadlani, Apaar
collection PubMed
description Hepatopulmonary syndrome is a phenomenon that results in an intrapulmonary shunt leading to dyspnea and hypoxemia with poor response to oxygen supplementation. It is now an indication for liver transplantation; however, some transplants result in subsequent pulmonary hypertension. Postulated mechanisms include unmasking of underlying pulmonary hypertension with liver transplant and increased pulmonary vascular resistance due to increased blood flow in hepatopulmonary syndrome. In this case, we describe pulmonary hypertension developing after orthotopic liver transplant in a cirrhotic patient with hepatopulmonary syndrome.
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spelling pubmed-91664582022-06-07 Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome Dadlani, Apaar Eiswerth, Michael Bosch, Armando Sharpe, Tyler Cureus Gastroenterology Hepatopulmonary syndrome is a phenomenon that results in an intrapulmonary shunt leading to dyspnea and hypoxemia with poor response to oxygen supplementation. It is now an indication for liver transplantation; however, some transplants result in subsequent pulmonary hypertension. Postulated mechanisms include unmasking of underlying pulmonary hypertension with liver transplant and increased pulmonary vascular resistance due to increased blood flow in hepatopulmonary syndrome. In this case, we describe pulmonary hypertension developing after orthotopic liver transplant in a cirrhotic patient with hepatopulmonary syndrome. Cureus 2022-05-04 /pmc/articles/PMC9166458/ /pubmed/35676995 http://dx.doi.org/10.7759/cureus.24740 Text en Copyright © 2022, Dadlani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Dadlani, Apaar
Eiswerth, Michael
Bosch, Armando
Sharpe, Tyler
Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome
title Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome
title_full Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome
title_fullStr Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome
title_full_unstemmed Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome
title_short Pulmonary Hypertension as a Rare Complication After Orthotopic Liver Transplant in a Patient With Non-alcoholic Steatohepatitis (NASH) Cirrhosis Complicated by Hepatopulmonary Syndrome
title_sort pulmonary hypertension as a rare complication after orthotopic liver transplant in a patient with non-alcoholic steatohepatitis (nash) cirrhosis complicated by hepatopulmonary syndrome
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166458/
https://www.ncbi.nlm.nih.gov/pubmed/35676995
http://dx.doi.org/10.7759/cureus.24740
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