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Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

BACKGROUND: The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, carboxyprimaquine, will support clinical pharmacometric ass...

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Detalles Bibliográficos
Autores principales:	Hanpithakpong, Warunee, Day, Nicholas P. J., White, Nicholas J., Tarning, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166498/ https://www.ncbi.nlm.nih.gov/pubmed/35659684 http://dx.doi.org/10.1186/s12936-022-04191-w

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