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A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation

Ventricular fibrillation is not known as a complication of metronidazole poisoning. Although some arrhythmias have been reported as a complication of metronidazole intake while taking antiarrhythmic medications, most such arrhythmias are possibly related to co-ingestion of drugs with metronidazole a...

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Autores principales: Elgassim, Mohamed Abdelgadir M, Saied, Amin Saied Sanosi, Mustafa, Moayad A, Abdelrahman, Amro, AlJaufi, Ibtesam, Salem, Waleed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166500/
https://www.ncbi.nlm.nih.gov/pubmed/35676987
http://dx.doi.org/10.7759/cureus.24728
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author Elgassim, Mohamed Abdelgadir M
Saied, Amin Saied Sanosi
Mustafa, Moayad A
Abdelrahman, Amro
AlJaufi, Ibtesam
Salem, Waleed
author_facet Elgassim, Mohamed Abdelgadir M
Saied, Amin Saied Sanosi
Mustafa, Moayad A
Abdelrahman, Amro
AlJaufi, Ibtesam
Salem, Waleed
author_sort Elgassim, Mohamed Abdelgadir M
collection PubMed
description Ventricular fibrillation is not known as a complication of metronidazole poisoning. Although some arrhythmias have been reported as a complication of metronidazole intake while taking antiarrhythmic medications, most such arrhythmias are possibly related to co-ingestion of drugs with metronidazole as it affects the metabolism of these drugs. In this case, ventricular fibrillation occurred in a young patient without preexisting medical conditions or any other known drug ingestion, which was never been reported before. We present a case of an 18-year-old male brought in by the ambulance service after attempting to end his life by overdosing on metronidazole. While being transported he developed ventricular fibrillation and received an electric shock, which reverted the episode. Laboratory investigations did not show any clear cause that might have precipitated his arrhythmia.
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spelling pubmed-91665002022-06-07 A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation Elgassim, Mohamed Abdelgadir M Saied, Amin Saied Sanosi Mustafa, Moayad A Abdelrahman, Amro AlJaufi, Ibtesam Salem, Waleed Cureus Cardiology Ventricular fibrillation is not known as a complication of metronidazole poisoning. Although some arrhythmias have been reported as a complication of metronidazole intake while taking antiarrhythmic medications, most such arrhythmias are possibly related to co-ingestion of drugs with metronidazole as it affects the metabolism of these drugs. In this case, ventricular fibrillation occurred in a young patient without preexisting medical conditions or any other known drug ingestion, which was never been reported before. We present a case of an 18-year-old male brought in by the ambulance service after attempting to end his life by overdosing on metronidazole. While being transported he developed ventricular fibrillation and received an electric shock, which reverted the episode. Laboratory investigations did not show any clear cause that might have precipitated his arrhythmia. Cureus 2022-05-04 /pmc/articles/PMC9166500/ /pubmed/35676987 http://dx.doi.org/10.7759/cureus.24728 Text en Copyright © 2022, Elgassim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Elgassim, Mohamed Abdelgadir M
Saied, Amin Saied Sanosi
Mustafa, Moayad A
Abdelrahman, Amro
AlJaufi, Ibtesam
Salem, Waleed
A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation
title A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation
title_full A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation
title_fullStr A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation
title_full_unstemmed A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation
title_short A Rare Case of Metronidazole Overdose Causing Ventricular Fibrillation
title_sort rare case of metronidazole overdose causing ventricular fibrillation
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166500/
https://www.ncbi.nlm.nih.gov/pubmed/35676987
http://dx.doi.org/10.7759/cureus.24728
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