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Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium
OBJECTIVES: Methotrexate (MTX) is an anchor drug for the treatment of rheumatoid arthritis (RA). However, the precise mechanisms by which MTX stalls RA progression and alleviates the ensuing disease effects remain unknown. The aim of the present study was to identify novel therapeutic target molecul...
Autores principales: | Shoda, Jumpei, Tanaka, Shigeru, Etori, Keishi, Hattori, Koto, Kasuya, Tadamichi, Ikeda, Kei, Maezawa, Yuko, Suto, Akira, Suzuki, Kotaro, Nakamura, Junichi, Maezawa, Yoshiro, Takemoto, Minoru, Betsholtz, Christer, Yokote, Koutaro, Ohtori, Seiji, Nakajima, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166515/ https://www.ncbi.nlm.nih.gov/pubmed/35659346 http://dx.doi.org/10.1186/s13075-022-02817-7 |
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