Cargando…

Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape

Hypoxia, a common feature of the tumor microenvironment in various types of cancers, weakens cytotoxic T cell function and causes recruitment of regulatory T cells, thereby reducing tumoral immunogenicity. Studies have demonstrated that hypoxia and hypoxia-inducible factors (HIFs) 1 and 2 alpha (HIF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Qinghua, You, Li, Nepovimova, Eugenie, Heger, Zbynek, Wu, Wenda, Kuca, Kamil, Adam, Vojtech
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166526/ https://www.ncbi.nlm.nih.gov/pubmed/35659268 http://dx.doi.org/10.1186/s13045-022-01292-6

Ejemplares similares

Type A Trichothecene Diacetoxyscirpenol-Induced Emesis Corresponds to Secretion of Peptide YY and Serotonin in Mink
por: Wu, Qinghua, et al.
Publicado: (2020)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
por: Huang, Xueqin, et al.
Publicado: (2023)

Recombinant ferritins for multimodal nanomedicine
por: Li, Yihao, et al.
Publicado: (2023)

A Review on the Synthesis and Bioactivity Aspects of Beauvericin, a Fusarium Mycotoxin
por: Wu, Qinghua, et al.
Publicado: (2018)

Combined Effect of Deoxynivalenol (DON) and Porcine Circovirus Type 2 (Pcv2) on Inflammatory Cytokine mRNA Expression
por: Gu, Chao, et al.
Publicado: (2021)

Chemistry and Toxicology of Major Bioactive Substances in Inocybe Mushrooms
por: Patocka, Jiri, et al.
Publicado: (2021)

Aflatoxin Detoxification Using Microorganisms and Enzymes
por: Guan, Yun, et al.
Publicado: (2021)

Malus domestica: A Review on Nutritional Features, Chemical Composition, Traditional and Medicinal Value
por: Patocka, Jiri, et al.
Publicado: (2020)

MicroRNA regulates the toxicological mechanism of four mycotoxins in vivo and in vitro
por: Chen, Jia, et al.
Publicado: (2022)

Marine Invertebrate Peptides: Antimicrobial Peptides
por: Wu, Ran, et al.
Publicado: (2021)

Flakka: New Dangerous Synthetic Cathinone on the Drug Scene
por: Patocka, Jiri, et al.
Publicado: (2020)

Deoxynivalenol (Vomitoxin)-Induced Anorexia Is Induced by the Release of Intestinal Hormones in Mice
por: Yue, Jianming, et al.
Publicado: (2021)

Bacillus velezensis A2 Inhibited the Cecal Inflammation Induced by Zearalenone by Regulating Intestinal Flora and Short-Chain Fatty Acids
por: Cai, Jing, et al.
Publicado: (2022)

Toxic Injury to Muscle Tissue of Rats Following Acute Oximes Exposure
por: Jaćević, Vesna, et al.
Publicado: (2019)

Acute Toxic Injuries of Rat’s Visceral Tissues Induced by Different Oximes
por: Jaćević, Vesna, et al.
Publicado: (2019)

The role of mTOR in age-related diseases
por: Chrienova, Zofia, et al.
Publicado: (2021)

Immune Evasion, a Potential Mechanism of Trichothecenes: New Insights into Negative Immune Regulations
por: Wu, Qinghua, et al.
Publicado: (2018)

Antioxidant agents against trichothecenes: new hints for oxidative stress treatment
por: Wu, Qinghua, et al.
Publicado: (2017)

Antidotal Potency of the Novel, Structurally Different Adsorbents in Rats Acutely Intoxicated with the T-2 Toxin
por: Jaćević, Vesna, et al.
Publicado: (2020)

Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies
por: Abou Khouzam, Raefa, et al.
Publicado: (2021)

Novel Group of AChE Reactivators—Synthesis, In Vitro Reactivation and Molecular Docking Study
por: Malinak, David, et al.
Publicado: (2018)

The oxazolomycin family: a review of current knowledge
por: Oleksak, Patrik, et al.
Publicado: (2020)

Hypoxia and Cellular Senescence, Emerging Toxic Mechanisms of Mycotoxins and Toxins: A New Understanding of the Negative Immune Regulations
por: Wu, Qinghua, et al.
Publicado: (2022)

The Significance of Reactive Oxygen Species and Antioxidant Defense System in Plants: A Concise Overview
por: Dumanović, Jelena, et al.
Publicado: (2021)

Hypoxia-Driven Immune Escape in the Tumor Microenvironment
por: Vito, Alyssa, et al.
Publicado: (2020)

Medicinal, nutritional, and nutraceutical potential of Sparassis crispa s. lat.: a review
por: Sharma, Neha, et al.
Publicado: (2022)

Optimization of Tilmicosin-Loaded Nanostructured Lipid Carriers Using Orthogonal Design for Overcoming Oral Administration Obstacle
por: Wen, Jia, et al.
Publicado: (2021)

Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune Escape
por: Chouaib, Salem, et al.
Publicado: (2012)

Simvastatin Inhibits Endotoxin-Induced Apoptosis in Liver and Spleen Through Up-Regulation of Survivin/NF-κB/p65 Expression
por: Nežić, Lana, et al.
Publicado: (2019)

Role of Vacha (Acorus calamus Linn.) in Neurological and Metabolic Disorders: Evidence from Ethnopharmacology, Phytochemistry, Pharmacology and Clinical Study
por: Sharma, Vineet, et al.
Publicado: (2020)

Flower-Based Green Synthesis of Metallic Nanoparticles: Applications beyond Fragrance
por: Kumar, Harsh, et al.
Publicado: (2020)

Rapamycin: Drug Repurposing in SARS-CoV-2 Infection
por: Patocka, Jiri, et al.
Publicado: (2021)

Red-Crowned Crane (Grus japonensis) Reproduction Was Improved by Inhibiting Mycotoxins with Montmorillonite in Feed
por: Liu, Dawei, et al.
Publicado: (2020)

Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon
por: Kuca, Kamil, et al.
Publicado: (2018)

Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach
por: da Silva, Jorge Alberto Valle, et al.
Publicado: (2019)

Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells’ Survival and Hindering Cytochrome C-Mediated Apoptosis
por: Nežić, Lana, et al.
Publicado: (2020)

Bioactive Compounds of Edible Fruits with Their Anti-Aging Properties: A Comprehensive Review to Prolong Human Life
por: Dhalaria, Rajni, et al.
Publicado: (2020)

Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
por: Jomova, Klaudia, et al.
Publicado: (2023)

Selective inhibitors for JNK signalling: a potential targeted therapy in cancer
por: Wu, Qinghua, et al.
Publicado: (2020)

Influence of Family Environment and Tobacco Addiction: A Short Report from a Post-Graduate Teaching Hospital, India
por: Sharma, Rohit, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oug53fhm744q7ev427uiclbsuh