A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment

BACKGROUND: A series of biochemical responses, including hypoxia and aseptic inflammation, occur in periodontal ligament cells (PDLCs) during periodontal tissue remodeling of orthodontic tooth movement (OTM). However, the role of long non-coding RNA (lncRNA) in these responses is still largely unkno...

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Detalles Bibliográficos
Autores principales: Wang, Chenxin, Yang, Qiaolin, Han, Yineng, Liu, Hao, Wang, Yue, Huang, Yiping, Zheng, Yunfei, Li, Weiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166574/
https://www.ncbi.nlm.nih.gov/pubmed/35659362
http://dx.doi.org/10.1186/s13287-022-02897-x

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