Human amniotic mesenchymal stem cells-derived IGFBP-3, DKK-3, and DKK-1 attenuate liver fibrosis through inhibiting hepatic stellate cell activation by blocking Wnt/β-catenin signaling pathway in mice

BACKGROUND: Liver fibrosis is an outcome of restoring process in chronic liver injury. Human amniotic mesenchymal stem cells (hAMSCs) derived from amniotic membrane have multilineage differentiation, immunosuppressive, and anti-inflammatory potential which makes them suitable for treating liver fibr...

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Detalles Bibliográficos
Autores principales: Liu, Quan-Wen, Ying, Yan-Min, Zhou, Jia-Xin, Zhang, Wen-Jie, Liu, Zhao-xiao, Jia, Bing-Bing, Gu, Hao-Cheng, Zhao, Chu-Yu, Guan, Xiao-Hui, Deng, Ke-Yu, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166579/
https://www.ncbi.nlm.nih.gov/pubmed/35659360
http://dx.doi.org/10.1186/s13287-022-02906-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166579/
https://www.ncbi.nlm.nih.gov/pubmed/35659360
http://dx.doi.org/10.1186/s13287-022-02906-z

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