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Human umbilical cord-derived mesenchymal stromal cells ameliorate aging-associated skeletal muscle atrophy and dysfunction by modulating apoptosis and mitochondrial damage in SAMP10 mice

BACKGROUND: Skeletal muscle mass and function losses in aging individuals are associated with quality of life deterioration and disability. Mesenchymal stromal cells exert immunomodulatory and anti-inflammatory effects and could yield beneficial effects in aging-related degenerative disease. METHODS...

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Detalles Bibliográficos
Autores principales: Piao, Limei, Huang, Zhe, Inoue, Aiko, Kuzuya, Masafumi, Cheng, Xian Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166592/
https://www.ncbi.nlm.nih.gov/pubmed/35659361
http://dx.doi.org/10.1186/s13287-022-02895-z

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