A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy

Upper gastrointestinal bleeding (UGIB) is a common and potentially life-threatening condition. Metastatic disease is an exceedingly rare cause of UGIB. We report the case of a 73-year-old man with high-grade B-cell lymphoma (HGBL) who presented for the initiation of chemotherapy and was found to be...

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Autores principales: Tanner, Samuel, Al Kazzi, Elie, Aslam, Rabail, Isenberg, Gerard, Cooper, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166593/
https://www.ncbi.nlm.nih.gov/pubmed/35676981
http://dx.doi.org/10.7759/cureus.24738
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author Tanner, Samuel
Al Kazzi, Elie
Aslam, Rabail
Isenberg, Gerard
Cooper, Gregory
author_facet Tanner, Samuel
Al Kazzi, Elie
Aslam, Rabail
Isenberg, Gerard
Cooper, Gregory
author_sort Tanner, Samuel
collection PubMed
description Upper gastrointestinal bleeding (UGIB) is a common and potentially life-threatening condition. Metastatic disease is an exceedingly rare cause of UGIB. We report the case of a 73-year-old man with high-grade B-cell lymphoma (HGBL) who presented for the initiation of chemotherapy and was found to be acutely anemic due to UGIB. An esophagogastroduodenoscopy (EGD) revealed multiple large, discrete, ulcerated, non-circumferential, and friable masses in the stomach. Biopsies were consistent with HGBL. The patient was urgently initiated on chemotherapy with the resolution of lesions on subsequent EGD. The rate of prevalence of gastric metastases is unknown, but it should be considered in patients with active malignancy who present with signs of UGIB.
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spelling pubmed-91665932022-06-07 A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy Tanner, Samuel Al Kazzi, Elie Aslam, Rabail Isenberg, Gerard Cooper, Gregory Cureus Internal Medicine Upper gastrointestinal bleeding (UGIB) is a common and potentially life-threatening condition. Metastatic disease is an exceedingly rare cause of UGIB. We report the case of a 73-year-old man with high-grade B-cell lymphoma (HGBL) who presented for the initiation of chemotherapy and was found to be acutely anemic due to UGIB. An esophagogastroduodenoscopy (EGD) revealed multiple large, discrete, ulcerated, non-circumferential, and friable masses in the stomach. Biopsies were consistent with HGBL. The patient was urgently initiated on chemotherapy with the resolution of lesions on subsequent EGD. The rate of prevalence of gastric metastases is unknown, but it should be considered in patients with active malignancy who present with signs of UGIB. Cureus 2022-05-04 /pmc/articles/PMC9166593/ /pubmed/35676981 http://dx.doi.org/10.7759/cureus.24738 Text en Copyright © 2022, Tanner et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Tanner, Samuel
Al Kazzi, Elie
Aslam, Rabail
Isenberg, Gerard
Cooper, Gregory
A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy
title A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy
title_full A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy
title_fullStr A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy
title_full_unstemmed A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy
title_short A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy
title_sort case of upper gastrointestinal bleeding due to metastatic high-grade b-cell lymphoma successfully treated with chemotherapy
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166593/
https://www.ncbi.nlm.nih.gov/pubmed/35676981
http://dx.doi.org/10.7759/cureus.24738
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