VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force

Hematogenous dissemination is a critical step in the evolution of local infection to systemic disease. The Lyme disease (LD) spirochete, which efficiently disseminates to multiple tissues, has provided a model for this process, in particular for the key early event of pathogen adhesion to the host v...

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Detalles Bibliográficos
Autores principales: Tan, Xi, Lin, Yi-Pin, Pereira, Michael J., Castellanos, Mildred, Hahn, Beth L., Anderson, Phillip, Coburn, Jenifer, Leong, John M., Chaconas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166660/
https://www.ncbi.nlm.nih.gov/pubmed/35605029
http://dx.doi.org/10.1371/journal.ppat.1010511

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