The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2

Castration-resistant prostate cancer (CRPC) is an aggressive lethal form of prostate cancer (PCa). Atraric acid (AA) not only inhibits the wild-type androgen receptor (AR) but also those AR mutants that confer therapy resistance to other clinically used AR antagonists, indicating a different mode of...

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Detalles Bibliográficos
Autores principales: Ehsani, Marzieh, Bartsch, Sophie, Rasa, Seyed Mohammad Mahdi, Dittmann, Jessica, Pungsrinont, Thanakorn, Neubert, Laura, Huettner, Soeren S., Kotolloshi, Roland, Schindler, Katrin, Ahmad, Aya, Mosig, Alexander S., Adam, Lisa, Ori, Alessandro, Neri, Francesco, Berndt, Alexander, Grimm, Marc-Oliver, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166678/
https://www.ncbi.nlm.nih.gov/pubmed/35513564
http://dx.doi.org/10.1038/s41388-022-02333-7

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