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Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque

The well documented association between obesity and the severity of SARS-CoV-2 infection raises the question of whether adipose tissue (AT) is impacted during this infection. Using a model of SARS-CoV-2 infection in cynomolgus macaques, we detected the virus within subcutaneous AT (SCAT) but not in...

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Detalles Bibliográficos
Autores principales: Olivo, Anaëlle, Marlin, Romain, Lazure, Thierry, Maisonnasse, Pauline, Bossevot, Laetitia, Mouanga, Christelliah, Lemaitre, Julien, Pourcher, Guillaume, Benoist, Stéphane, Le Grand, Roger, Lambotte, Olivier, Dereuddre-Bosquet, Nathalie, Bourgeois, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166782/
https://www.ncbi.nlm.nih.gov/pubmed/35661814
http://dx.doi.org/10.1038/s42003-022-03503-9