Cargando…

Nobiletin resolves left ventricular and renal changes in 2K-1C hypertensive rats

This study investigated the effects of nobiletin on cardiorenal changes and the underlying mechanisms involved in two-kidney, one-clip (2K-1C) hypertension. 2K-1C rats were treated with nobiletin (15 or 30 mg/kg/day) or losartan (10 mg/kg/day) for 4 weeks (n = 8/group). Nobiletin (30 mg/kg) reduced...

Descripción completa

Detalles Bibliográficos
Autores principales: Iampanichakul, Metee, Poasakate, Anuson, Potue, Prapassorn, Rattanakanokchai, Siwayu, Maneesai, Putcharawipa, Prachaney, Parichat, Settheetham-Ishida, Wannapa, Pakdeechote, Poungrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166784/
https://www.ncbi.nlm.nih.gov/pubmed/35662276
http://dx.doi.org/10.1038/s41598-022-13513-6