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TCRαβ-Depleted Haploidentical Grafts Are a Safe Alternative to HLA-Matched Unrelated Donor Stem Cell Transplants for Infants with Severe Combined Immunodeficiency

Hematopoietic stem cell transplantation and gene therapy are the only curative therapies for severe combined immunodeficiency (SCID). In patients lacking a matched donor, TCRαβ/CD19-depleted haploidentical family donor transplant (TCRαβ-HaploSCT) is a promising strategy. Conditioned transplant in SC...

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Detalles Bibliográficos
Autores principales:	Tsilifis, Christo, Lum, Su Han, Nademi, Zohreh, Hambleton, Sophie, Flood, Terence J., Williams, Eleri J., Owens, Stephen, Abinun, Mario, Cant, Andrew J., Slatter, Mary A., Gennery, Andrew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166847/ https://www.ncbi.nlm.nih.gov/pubmed/35305204 http://dx.doi.org/10.1007/s10875-022-01239-z

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