Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation

Opioids are widely used in chronic pain management, despite major concerns about their risk of adverse events, particularly abuse, misuse, and respiratory depression from overdose. Multi-mechanistic opioids, such as tapentadol and buprenorphine, have been widely studied as a valid alternative to tra...

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Detalles Bibliográficos
Autores principales: Coluzzi, Flaminia, Rullo, Laura, Scerpa, Maria Sole, Losapio, Loredana Maria, Rocco, Monica, Billeci, Domenico, Candeletti, Sanzio, Romualdi, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166888/
https://www.ncbi.nlm.nih.gov/pubmed/35616826
http://dx.doi.org/10.1007/s40263-022-00924-2

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