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Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China

BACKGROUND: Pulmonary tuberculosis (PTB) is a severe infection, and its factors that influence survival have not been explored in some developed regions. Therefore, this study aimed to identify the factors that influence TB survival in China. METHODS: We acquired data of PTB deaths through matching...

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Autores principales: Liu, Kui, Ai, Liyun, Pan, Jin, Fei, Fangrong, Chen, Songhua, Zhang, Yu, Wang, Wei, Wu, Qian, Chen, Bin, Pan, Junhang, Zhong, Jieming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166951/
https://www.ncbi.nlm.nih.gov/pubmed/35669895
http://dx.doi.org/10.2147/RMHP.S368593
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author Liu, Kui
Ai, Liyun
Pan, Jin
Fei, Fangrong
Chen, Songhua
Zhang, Yu
Wang, Wei
Wu, Qian
Chen, Bin
Pan, Junhang
Zhong, Jieming
author_facet Liu, Kui
Ai, Liyun
Pan, Jin
Fei, Fangrong
Chen, Songhua
Zhang, Yu
Wang, Wei
Wu, Qian
Chen, Bin
Pan, Junhang
Zhong, Jieming
author_sort Liu, Kui
collection PubMed
description BACKGROUND: Pulmonary tuberculosis (PTB) is a severe infection, and its factors that influence survival have not been explored in some developed regions. Therefore, this study aimed to identify the factors that influence TB survival in China. METHODS: We acquired data of PTB deaths through matching two manage systems of PTB and mortality surveillance. The Kaplan–Meier method and Cox regression model were used to identify the significant factors under various survival times. RESULTS: A total of 283 deaths were caused by PTB, in which 53.4% occurred during the first year. In the Cox regression model, regular sputum smear test could reduce the risk of PTB death from the result of one-, three-, and five-year survival; and history of PTB treatment could decline the risk of PTB death in the first year. Additionally, age of “75–90 years” and positive result of sputum smear test significantly increased the risk of PTB death for the findings of three- and five-year survival, while age of “60–75 years” could increase the probability of PTB death for five-year survival. CONCLUSION: To reduce PTB deaths, more attention should be paid to the older group especially in the first year. Regular sputum smear test could effectively reduce the mortality of PTB cases. More evidence-based interventions should be implemented to enhance the survival of patients with PTB.
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spelling pubmed-91669512022-06-05 Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China Liu, Kui Ai, Liyun Pan, Jin Fei, Fangrong Chen, Songhua Zhang, Yu Wang, Wei Wu, Qian Chen, Bin Pan, Junhang Zhong, Jieming Risk Manag Healthc Policy Original Research BACKGROUND: Pulmonary tuberculosis (PTB) is a severe infection, and its factors that influence survival have not been explored in some developed regions. Therefore, this study aimed to identify the factors that influence TB survival in China. METHODS: We acquired data of PTB deaths through matching two manage systems of PTB and mortality surveillance. The Kaplan–Meier method and Cox regression model were used to identify the significant factors under various survival times. RESULTS: A total of 283 deaths were caused by PTB, in which 53.4% occurred during the first year. In the Cox regression model, regular sputum smear test could reduce the risk of PTB death from the result of one-, three-, and five-year survival; and history of PTB treatment could decline the risk of PTB death in the first year. Additionally, age of “75–90 years” and positive result of sputum smear test significantly increased the risk of PTB death for the findings of three- and five-year survival, while age of “60–75 years” could increase the probability of PTB death for five-year survival. CONCLUSION: To reduce PTB deaths, more attention should be paid to the older group especially in the first year. Regular sputum smear test could effectively reduce the mortality of PTB cases. More evidence-based interventions should be implemented to enhance the survival of patients with PTB. Dove 2022-05-31 /pmc/articles/PMC9166951/ /pubmed/35669895 http://dx.doi.org/10.2147/RMHP.S368593 Text en © 2022 Liu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Liu, Kui
Ai, Liyun
Pan, Jin
Fei, Fangrong
Chen, Songhua
Zhang, Yu
Wang, Wei
Wu, Qian
Chen, Bin
Pan, Junhang
Zhong, Jieming
Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China
title Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China
title_full Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China
title_fullStr Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China
title_full_unstemmed Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China
title_short Survival Analysis and Associated Factors for Pulmonary Tuberculosis Death: Evidence from the Information System of Tuberculosis Disease and Mortality Surveillance in China
title_sort survival analysis and associated factors for pulmonary tuberculosis death: evidence from the information system of tuberculosis disease and mortality surveillance in china
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166951/
https://www.ncbi.nlm.nih.gov/pubmed/35669895
http://dx.doi.org/10.2147/RMHP.S368593
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