Cargando…

Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature

Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Martins, Tiago, Umar, Jalaluddin, Groudan, Kevin, Bharadwaj, Hariharan S., Desilets, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167136/
https://www.ncbi.nlm.nih.gov/pubmed/35669380
http://dx.doi.org/10.1155/2022/5703407
_version_ 1784720765445210112
author Martins, Tiago
Umar, Jalaluddin
Groudan, Kevin
Bharadwaj, Hariharan S.
Desilets, David
author_facet Martins, Tiago
Umar, Jalaluddin
Groudan, Kevin
Bharadwaj, Hariharan S.
Desilets, David
author_sort Martins, Tiago
collection PubMed
description Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. The ileal biopsy specimens were nonspecific, and the patient began a trial of corticosteroid treatment for suspected Crohn's disease. A repeat colonoscopy yielded biopsies that were positive for malignancy. The patient then underwent an exploratory laparotomy which led to the diagnosis of SRCC. Given their similar presentations and the extreme rarity of this unusual malignancy, it can be difficult to differentiate between new-onset Crohn's disease and SRCC. A review of the literature was conducted to provide us with an improved understanding of previously documented cases of SRCC.
format Online
Article
Text
id pubmed-9167136
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-91671362022-06-05 Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature Martins, Tiago Umar, Jalaluddin Groudan, Kevin Bharadwaj, Hariharan S. Desilets, David Case Rep Gastrointest Med Case Report Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. The ileal biopsy specimens were nonspecific, and the patient began a trial of corticosteroid treatment for suspected Crohn's disease. A repeat colonoscopy yielded biopsies that were positive for malignancy. The patient then underwent an exploratory laparotomy which led to the diagnosis of SRCC. Given their similar presentations and the extreme rarity of this unusual malignancy, it can be difficult to differentiate between new-onset Crohn's disease and SRCC. A review of the literature was conducted to provide us with an improved understanding of previously documented cases of SRCC. Hindawi 2022-05-28 /pmc/articles/PMC9167136/ /pubmed/35669380 http://dx.doi.org/10.1155/2022/5703407 Text en Copyright © 2022 Tiago Martins et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Martins, Tiago
Umar, Jalaluddin
Groudan, Kevin
Bharadwaj, Hariharan S.
Desilets, David
Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
title Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
title_full Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
title_fullStr Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
title_full_unstemmed Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
title_short Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
title_sort mucinous signet-cell adenocarcinoma of the ileum: a diagnostic challenge—case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167136/
https://www.ncbi.nlm.nih.gov/pubmed/35669380
http://dx.doi.org/10.1155/2022/5703407
work_keys_str_mv AT martinstiago mucinoussignetcelladenocarcinomaoftheileumadiagnosticchallengecasereportandreviewoftheliterature
AT umarjalaluddin mucinoussignetcelladenocarcinomaoftheileumadiagnosticchallengecasereportandreviewoftheliterature
AT groudankevin mucinoussignetcelladenocarcinomaoftheileumadiagnosticchallengecasereportandreviewoftheliterature
AT bharadwajhariharans mucinoussignetcelladenocarcinomaoftheileumadiagnosticchallengecasereportandreviewoftheliterature
AT desiletsdavid mucinoussignetcelladenocarcinomaoftheileumadiagnosticchallengecasereportandreviewoftheliterature