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Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature
Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. T...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167136/ https://www.ncbi.nlm.nih.gov/pubmed/35669380 http://dx.doi.org/10.1155/2022/5703407 |
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author | Martins, Tiago Umar, Jalaluddin Groudan, Kevin Bharadwaj, Hariharan S. Desilets, David |
author_facet | Martins, Tiago Umar, Jalaluddin Groudan, Kevin Bharadwaj, Hariharan S. Desilets, David |
author_sort | Martins, Tiago |
collection | PubMed |
description | Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. The ileal biopsy specimens were nonspecific, and the patient began a trial of corticosteroid treatment for suspected Crohn's disease. A repeat colonoscopy yielded biopsies that were positive for malignancy. The patient then underwent an exploratory laparotomy which led to the diagnosis of SRCC. Given their similar presentations and the extreme rarity of this unusual malignancy, it can be difficult to differentiate between new-onset Crohn's disease and SRCC. A review of the literature was conducted to provide us with an improved understanding of previously documented cases of SRCC. |
format | Online Article Text |
id | pubmed-9167136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-91671362022-06-05 Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature Martins, Tiago Umar, Jalaluddin Groudan, Kevin Bharadwaj, Hariharan S. Desilets, David Case Rep Gastrointest Med Case Report Malignancies of the small intestine are rare. Signet-ring cell carcinoma (SRCC) is one of the rarest forms of adenocarcinoma that can arise in the small intestines. We present a case of a patient who originally presented with abdominal pain and radiographic findings suggestive of ileal congestion. The ileal biopsy specimens were nonspecific, and the patient began a trial of corticosteroid treatment for suspected Crohn's disease. A repeat colonoscopy yielded biopsies that were positive for malignancy. The patient then underwent an exploratory laparotomy which led to the diagnosis of SRCC. Given their similar presentations and the extreme rarity of this unusual malignancy, it can be difficult to differentiate between new-onset Crohn's disease and SRCC. A review of the literature was conducted to provide us with an improved understanding of previously documented cases of SRCC. Hindawi 2022-05-28 /pmc/articles/PMC9167136/ /pubmed/35669380 http://dx.doi.org/10.1155/2022/5703407 Text en Copyright © 2022 Tiago Martins et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Martins, Tiago Umar, Jalaluddin Groudan, Kevin Bharadwaj, Hariharan S. Desilets, David Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature |
title | Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature |
title_full | Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature |
title_fullStr | Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature |
title_full_unstemmed | Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature |
title_short | Mucinous Signet-Cell Adenocarcinoma of the Ileum: A Diagnostic Challenge—Case Report and Review of the Literature |
title_sort | mucinous signet-cell adenocarcinoma of the ileum: a diagnostic challenge—case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167136/ https://www.ncbi.nlm.nih.gov/pubmed/35669380 http://dx.doi.org/10.1155/2022/5703407 |
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