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Binding Stability of Antibody—α-Synuclein Complexes Predicts the Protective Efficacy of Anti-α-synuclein Antibodies

Spreading of alpha-synuclein (αSyn) may play an important role in Parkinson’s disease and related synucleinopathies. Passive immunization with anti-αSyn antibodies is a promising method to slow down the spreading process and thereby the progression of synucleinopathies. Currently, it remains elusive...

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Detalles Bibliográficos
Autores principales:	Höllerhage, Matthias, Wolff, Andreas, Chakroun, Tasnim, Evsyukov, Valentin, Duan, Linghan, Chua, Oscar Wing-Ho, Tang, Qilin, Koeglsperger, Thomas, Höglinger, Günter U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167191/ https://www.ncbi.nlm.nih.gov/pubmed/35460053 http://dx.doi.org/10.1007/s12035-022-02824-4

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