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Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice

Charcot-Marie-Tooth disease type 1A (CMT1A), caused by duplication of the peripheral myelin protein 22 (PMP22) gene, and CMT1B, caused by mutations in myelin protein zero (MPZ) gene, are the two most common forms of demyelinating CMT (CMT1), and no treatments are available for either. Prior studies...

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Detalles Bibliográficos
Autores principales: Bai, Yunhong, Treins, Caroline, Volpi, Vera G., Scapin, Cristina, Ferri, Cinzia, Mastrangelo, Rosa, Touvier, Thierry, Florio, Francesca, Bianchi, Francesca, Del Carro, Ubaldo, Baas, Frank F., Wang, David, Miniou, Pierre, Guedat, Philippe, Shy, Michael E., D’Antonio, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167212/
https://www.ncbi.nlm.nih.gov/pubmed/35501630
http://dx.doi.org/10.1007/s12035-022-02838-y