First-in-Human Phase I Study of the Novel Injectable Calcimimetic Agent Upacicalcet in Healthy Adult Japanese Participants

BACKGROUND AND OBJECTIVE: Upacicalcet sodium hydrate is a novel small-molecule calcimimetic and has potential as a therapeutic agent for secondary hyperparathyroidism. We assessed the pharmacokinetics, pharmacodynamics, safety, and tolerability of a single intravenous dose of upacicalcet in Japanese...

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Detalles Bibliográficos
Autores principales: Koiwa, Fumihiko, Yazawa, Rie, Fukagawa, Masafumi, Honda, Daisuke, Akizawa, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167405/
https://www.ncbi.nlm.nih.gov/pubmed/35338469
http://dx.doi.org/10.1007/s40268-022-00385-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167405/
https://www.ncbi.nlm.nih.gov/pubmed/35338469
http://dx.doi.org/10.1007/s40268-022-00385-4

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