Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report

BACKGROUND: Catheter-related bloodstream infection (CRBSI), caused by rapidly growing mycobacteria (RGM), is a rare infectious complication in hematopoietic stem cell transplant (HSCT) recipients and can often be misdiagnosed as Gram-positive rod (GPR) bacteremia. CASE PRESENTATION: We present a cas...

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Autores principales: Muranaka, Emiri, Hase, Ryota, Utsu, Yoshikazu, Watari, Tomohisa, Otsuka, Yoshihito, Hosokawa, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167550/
https://www.ncbi.nlm.nih.gov/pubmed/35659262
http://dx.doi.org/10.1186/s12879-022-07495-z
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author Muranaka, Emiri
Hase, Ryota
Utsu, Yoshikazu
Watari, Tomohisa
Otsuka, Yoshihito
Hosokawa, Naoto
author_facet Muranaka, Emiri
Hase, Ryota
Utsu, Yoshikazu
Watari, Tomohisa
Otsuka, Yoshihito
Hosokawa, Naoto
author_sort Muranaka, Emiri
collection PubMed
description BACKGROUND: Catheter-related bloodstream infection (CRBSI), caused by rapidly growing mycobacteria (RGM), is a rare infectious complication in hematopoietic stem cell transplant (HSCT) recipients and can often be misdiagnosed as Gram-positive rod (GPR) bacteremia. CASE PRESENTATION: We present a case of CRBSI caused by Mycobacterium wolinskyi, a rare RGM, in a 44-year-old female patient who received an umbilical cord blood transplant. CONCLUSIONS: Rapidly growing mycobacteria can stain as GPRs and may grow in routine blood culture media after 3–4 days of incubation. These features are not widely known to clinicians, and acid-fast staining is therefore recommended when unidentifiable GPRs are detected in blood cultures, especially in immunocompromised patients, such as those with hematologic malignancies or intravascular devices.
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spelling pubmed-91675502022-06-06 Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report Muranaka, Emiri Hase, Ryota Utsu, Yoshikazu Watari, Tomohisa Otsuka, Yoshihito Hosokawa, Naoto BMC Infect Dis Case Report BACKGROUND: Catheter-related bloodstream infection (CRBSI), caused by rapidly growing mycobacteria (RGM), is a rare infectious complication in hematopoietic stem cell transplant (HSCT) recipients and can often be misdiagnosed as Gram-positive rod (GPR) bacteremia. CASE PRESENTATION: We present a case of CRBSI caused by Mycobacterium wolinskyi, a rare RGM, in a 44-year-old female patient who received an umbilical cord blood transplant. CONCLUSIONS: Rapidly growing mycobacteria can stain as GPRs and may grow in routine blood culture media after 3–4 days of incubation. These features are not widely known to clinicians, and acid-fast staining is therefore recommended when unidentifiable GPRs are detected in blood cultures, especially in immunocompromised patients, such as those with hematologic malignancies or intravascular devices. BioMed Central 2022-06-04 /pmc/articles/PMC9167550/ /pubmed/35659262 http://dx.doi.org/10.1186/s12879-022-07495-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Muranaka, Emiri
Hase, Ryota
Utsu, Yoshikazu
Watari, Tomohisa
Otsuka, Yoshihito
Hosokawa, Naoto
Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
title Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
title_full Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
title_fullStr Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
title_full_unstemmed Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
title_short Catheter-related bloodstream Mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
title_sort catheter-related bloodstream mycobacterium wolinskyi infection in an umbilical cord blood transplant recipient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167550/
https://www.ncbi.nlm.nih.gov/pubmed/35659262
http://dx.doi.org/10.1186/s12879-022-07495-z
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