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The ASIC3-M-CSF-M2 macrophage-positive feedback loop modulates fibroblast-to-myofibroblast differentiation in skin fibrosis pathogenesis

Inflammation is one of the main pathological features leading to skin fibrosis and a key factor leading to the progression of skin fibrosis. Acidosis caused by a decrease in extracellular pH is a sign of the inflammatory process. Acid-sensing ion channels (ASICs) are ligand-gated ion channels on the...

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Detalles Bibliográficos
Autores principales:	Wu, Jun-Jie, Sun, Zi-Li, Liu, Si-Yu, Chen, Zhong-Hua, Yuan, Zheng-Dong, Zou, Ming-Li, Teng, Ying-Ying, Li, Yue-Yue, Guo, Dan-Yang, Yuan, Feng-Lai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167818/ https://www.ncbi.nlm.nih.gov/pubmed/35661105 http://dx.doi.org/10.1038/s41419-022-04981-9

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