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Systemic DNA/RNA heteroduplex oligonucleotide administration for regulating the gene expression of dorsal root ganglion and sciatic nerve

Neuropathic pain, a heterogeneous condition, affects 7%–10% of the general population. To date, efficacious and safe therapeutic approaches remain limited. Antisense oligonucleotide (ASO) therapy has opened the door to treat spinal muscular atrophy, with many ongoing clinical studies determining its...

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Detalles Bibliográficos
Autores principales:	Kaburagi, Hidetoshi, Nagata, Tetsuya, Enomoto, Mitsuhiro, Hirai, Takashi, Ohyagi, Masaki, Ihara, Kensuke, Yoshida-Tanaka, Kie, Ebihara, Satoe, Asada, Ken, Yokoyama, Hiroyuki, Okawa, Atsushi, Yokota, Takanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167871/ https://www.ncbi.nlm.nih.gov/pubmed/35694210 http://dx.doi.org/10.1016/j.omtn.2022.05.006

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