Severe childhood lichen planus pemphigoides after hepatitis A vaccination

BACKGROUND: Lichen planus (LP) pemphigoides (LPP) is a very rare autoimmune bullous disorder, that is, exceptional in children. CASE REPORT: We report a case of LP pemphigoides with severe cutaneous and mucosal involvement in an 8‐year‐old girl who consulted for multiple vesicular and bullous lesion...

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Detalles Bibliográficos
Autores principales: Lahouel, M., Aounallah, A., Mokni, S., Sriha, B., Belajouza, C., Denguezli, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168010/
https://www.ncbi.nlm.nih.gov/pubmed/35677923
http://dx.doi.org/10.1002/ski2.94
Descripción
Sumario:BACKGROUND: Lichen planus (LP) pemphigoides (LPP) is a very rare autoimmune bullous disorder, that is, exceptional in children. CASE REPORT: We report a case of LP pemphigoides with severe cutaneous and mucosal involvement in an 8‐year‐old girl who consulted for multiple vesicular and bullous lesions associated with shiny erythematous‐purple plaques. The eruption occurred 2 months after vaccination against hepatitis A virus. The diagnosis of LP pemphigoides was confirmed by histopathology and immunofluorescence examination. The patient received oral corticosteroid therapy with rapid improvement. CONCLUSION: To our knowledge, this is the first report of LPP following hepatitis A vaccination, among adults and children.

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