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Structural Insight Into Ryanodine Receptor Channelopathies
The ryanodine receptors (RyRs) are large cation-selective ligand-gated channels that are expressed in the sarcoplasmic reticulum (SR) membrane. They mediate the controlled release of Ca(2+) from SR and play an important role in many cellular processes. The mutations in RyRs are associated with sever...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168041/ https://www.ncbi.nlm.nih.gov/pubmed/35677449 http://dx.doi.org/10.3389/fphar.2022.897494 |