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Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series
INTRODUCTION AND IMPORTANCE: Due to its high collagen, good adherence to wound bed, and great wound healing properties, Tilapia (Oreochromis niloticus) skin has been studied as a biomaterial in regenerative medicine, including as a burn dressing. This paper evaluated the efficacy of tilapia skin xen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168165/ http://dx.doi.org/10.1016/j.ijscr.2022.107240 |
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author | Putri, Nandita Melati Kreshanti, Prasetyanugraheni Syarif, Akhmad Noviandi Duhita, Gadia Ayundya Johanna, Nadya Wardhana, Aditya |
author_facet | Putri, Nandita Melati Kreshanti, Prasetyanugraheni Syarif, Akhmad Noviandi Duhita, Gadia Ayundya Johanna, Nadya Wardhana, Aditya |
author_sort | Putri, Nandita Melati |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Due to its high collagen, good adherence to wound bed, and great wound healing properties, Tilapia (Oreochromis niloticus) skin has been studied as a biomaterial in regenerative medicine, including as a burn dressing. This paper evaluated the efficacy of tilapia skin xenograft as a temporary full-thickness burn dressing. METHODS: Four acute burn patients aged 23–48 years old with total body surface area ranging from 27.5 to 37% with a similar burn area on both sides of the limbs were included. Each limb was dressed in tilapia skin or paraffin-impregnated gauze. Two subjects passed away due to septic shock. All limbs treated with tilapia skin xenograft required fewer dressing changes compared to the limbs treated with paraffin-impregnated gauze. All remaining subjects underwent skin autograft transplantation surgery on the eleventh day after the debridement surgery. No allergic reaction was found in any of the subjects. OUTCOMES: The tilapia xenograft performed better in controlling and containing the exudates compared to the paraffin-impregnated gauze, as reflected in the fewer dressing changes needed. The cause of death of the two patients was questionable as both of them have severe pneumonia and COVID-19 still could not be ruled out yet. CONCLUSION: The tilapia skin xenograft was not inferior to the standard paraffin-impregnated gauze for full-thickness burn dressing in terms of time needed for wound bed preparation for autograft surgery. |
format | Online Article Text |
id | pubmed-9168165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91681652022-06-07 Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series Putri, Nandita Melati Kreshanti, Prasetyanugraheni Syarif, Akhmad Noviandi Duhita, Gadia Ayundya Johanna, Nadya Wardhana, Aditya Int J Surg Case Rep Case Series INTRODUCTION AND IMPORTANCE: Due to its high collagen, good adherence to wound bed, and great wound healing properties, Tilapia (Oreochromis niloticus) skin has been studied as a biomaterial in regenerative medicine, including as a burn dressing. This paper evaluated the efficacy of tilapia skin xenograft as a temporary full-thickness burn dressing. METHODS: Four acute burn patients aged 23–48 years old with total body surface area ranging from 27.5 to 37% with a similar burn area on both sides of the limbs were included. Each limb was dressed in tilapia skin or paraffin-impregnated gauze. Two subjects passed away due to septic shock. All limbs treated with tilapia skin xenograft required fewer dressing changes compared to the limbs treated with paraffin-impregnated gauze. All remaining subjects underwent skin autograft transplantation surgery on the eleventh day after the debridement surgery. No allergic reaction was found in any of the subjects. OUTCOMES: The tilapia xenograft performed better in controlling and containing the exudates compared to the paraffin-impregnated gauze, as reflected in the fewer dressing changes needed. The cause of death of the two patients was questionable as both of them have severe pneumonia and COVID-19 still could not be ruled out yet. CONCLUSION: The tilapia skin xenograft was not inferior to the standard paraffin-impregnated gauze for full-thickness burn dressing in terms of time needed for wound bed preparation for autograft surgery. Elsevier 2022-05-25 /pmc/articles/PMC9168165/ http://dx.doi.org/10.1016/j.ijscr.2022.107240 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Series Putri, Nandita Melati Kreshanti, Prasetyanugraheni Syarif, Akhmad Noviandi Duhita, Gadia Ayundya Johanna, Nadya Wardhana, Aditya Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series |
title | Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series |
title_full | Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series |
title_fullStr | Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series |
title_full_unstemmed | Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series |
title_short | Efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: A case series |
title_sort | efficacy of tilapia skin xenograft compared to paraffin-impregnated gauze as a full-thickness burn dressing after excisional debridement: a case series |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168165/ http://dx.doi.org/10.1016/j.ijscr.2022.107240 |
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