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Therapeutical Significance of Serpina3n Subsequent Cerebral Ischemia via Cytotoxic Granzyme B Inactivation

Ischemic stroke is a devastating CNS insult with few clinical cures. Poor understanding of underlying mechanistic network is the primary limitation to develop novel curative therapies. Extracellular accumulation of granzyme B subsequent ischemia promotes neurodegeneration. Inhibition of granzyme B c...

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Detalles Bibliográficos
Autores principales:	Aslam, Mehwish Saba, Aslam, Mobeena Saba, Aslam, Komal Saba, Iqbal, Asia, Yuan, Liudi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168188/ https://www.ncbi.nlm.nih.gov/pubmed/35677097 http://dx.doi.org/10.1155/2022/1557010

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