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Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes

The study is aimed at evaluating corneal epithelial thickness changes associated with overnight orthokeratology (ortho-K). In this retrospective study, epithelial thickness was measured using optical coherence tomography (OCT) before and after 1 day, 1 week, 1 month, and 3 months ortho-K nightly len...

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Autores principales: Qu, Dongyi, Zhou, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168212/
https://www.ncbi.nlm.nih.gov/pubmed/35677633
http://dx.doi.org/10.1155/2022/3361172
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author Qu, Dongyi
Zhou, Yuehua
author_facet Qu, Dongyi
Zhou, Yuehua
author_sort Qu, Dongyi
collection PubMed
description The study is aimed at evaluating corneal epithelial thickness changes associated with overnight orthokeratology (ortho-K). In this retrospective study, epithelial thickness was measured using optical coherence tomography (OCT) before and after 1 day, 1 week, 1 month, and 3 months ortho-K nightly lens wear. Compared with pre-orthokeratology measurements, central (2 mm) corneal epithelium thickness was significantly reduced at 1 day, 1 week, 1 month, and 3 months with ortho-K (P < 0.05). Paracentral (2 mm~5 mm annular ring) epithelial thickness was also significantly reduced at superior temporal, inferior temporal, temporal, and inferior locations after ortho-K (P < 0.05), while midperipheral (5 mm~6 mm annular ring) epithelial thickness was greater post- than pre-ortho-K at superior, superior temporal, inferior temporal, inferior, and inferior nasal locations (P < 0.05). In other zones, superior, superior nasal, nasal, and inferior nasal in paracentral annular ring and temporal and superior nasal in midperipheral ring, epithelial thickness underwent no significant change. Ortho-K lens wear caused the central corneal epitheliums to thin. The temporal half zones become thinner in paracentral zones and thicker in midperipheral zones.
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spelling pubmed-91682122022-06-07 Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes Qu, Dongyi Zhou, Yuehua Dis Markers Research Article The study is aimed at evaluating corneal epithelial thickness changes associated with overnight orthokeratology (ortho-K). In this retrospective study, epithelial thickness was measured using optical coherence tomography (OCT) before and after 1 day, 1 week, 1 month, and 3 months ortho-K nightly lens wear. Compared with pre-orthokeratology measurements, central (2 mm) corneal epithelium thickness was significantly reduced at 1 day, 1 week, 1 month, and 3 months with ortho-K (P < 0.05). Paracentral (2 mm~5 mm annular ring) epithelial thickness was also significantly reduced at superior temporal, inferior temporal, temporal, and inferior locations after ortho-K (P < 0.05), while midperipheral (5 mm~6 mm annular ring) epithelial thickness was greater post- than pre-ortho-K at superior, superior temporal, inferior temporal, inferior, and inferior nasal locations (P < 0.05). In other zones, superior, superior nasal, nasal, and inferior nasal in paracentral annular ring and temporal and superior nasal in midperipheral ring, epithelial thickness underwent no significant change. Ortho-K lens wear caused the central corneal epitheliums to thin. The temporal half zones become thinner in paracentral zones and thicker in midperipheral zones. Hindawi 2022-05-29 /pmc/articles/PMC9168212/ /pubmed/35677633 http://dx.doi.org/10.1155/2022/3361172 Text en Copyright © 2022 Dongyi Qu and Yuehua Zhou. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Qu, Dongyi
Zhou, Yuehua
Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
title Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
title_full Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
title_fullStr Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
title_full_unstemmed Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
title_short Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
title_sort post-ortho-k corneal epithelium changes in myopic eyes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168212/
https://www.ncbi.nlm.nih.gov/pubmed/35677633
http://dx.doi.org/10.1155/2022/3361172
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